Catechol-O-methyl transferase and schizophrenia
The COMT Val108/158Met polymorphism is an almost irresistible target for genetic investigations, and combined worldwide, many thousands of cases and controls have now been studied, yielding positive and negative results. Heterogeniety of patient population has undoubtedly contributed to these incons...
| Permalink: | http://skupni.nsk.hr/Record/ffzg.KOHA-OAI-FFZG:308758/Details |
|---|---|
| Matična publikacija: |
Psychiatria Danubina 22 (2010), 2 ; str. 270-274 |
| Glavni autori: | Šagud (-), Marina (Author), Mück-Seler, Dorotea, Mihaljević-Peleš, Alma, Vuksan-Čusa, Bjanka Jakovljević, Miro, Pivac, Nela |
| Vrsta građe: | Članak |
| Jezik: | eng |
| Online pristup: |
http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=84650 |
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| 245 | 1 | 0 | |a Catechol-O-methyl transferase and schizophrenia / |c Šagud ; Marina ; Mück-Seler, Dorotea ; Mihaljević-Peleš, Alma ; Vuksan-Čusa, Bjanka ; Jakovljević, Miro ; Pivac, Nela. |
| 246 | 3 | |i Naslov na engleskom: |a Catechol-O-methyl transferase and schizophrenia | |
| 300 | |a 270-274 |f str. | ||
| 363 | |a 22 |b 2 |i 2010 | ||
| 520 | |a The COMT Val108/158Met polymorphism is an almost irresistible target for genetic investigations, and combined worldwide, many thousands of cases and controls have now been studied, yielding positive and negative results. Heterogeniety of patient population has undoubtedly contributed to these inconsistent results. While the high activity Val allele is weakly, if at all, associated with the increased risk for schizophrenia, its interaction with other candidate genes, environmental factors, such as smoking, antipsychotic efficacy and adverse events, as well as its role in cognitive (dys)function is an exciting area for the future research. | ||
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| 693 | |a Catechol-O-methyl transferase, COMT variants, schizophrenia |l hrv |2 crosbi | ||
| 693 | |a Catechol-O-methyl transferase, COMT variants, schizophrenia |l eng |2 crosbi | ||
| 700 | 1 | |a Marina |4 aut | |
| 700 | 1 | |a Mück-Seler, Dorotea |4 aut | |
| 700 | 1 | |a Mihaljević-Peleš, Alma |4 aut | |
| 700 | 1 | |a Vuksan-Čusa, Bjanka |4 aut |a Jakovljević, Miro | |
| 700 | 1 | |a Pivac, Nela |4 aut | |
| 773 | 0 | |t Psychiatria Danubina |x 0353-5053 |g 22 (2010), 2 ; str. 270-274 | |
| 856 | |u http://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=84650 | ||
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