N-glycosylation of recombinant therapeutic glycoproteins in plant systems
Transgenic plants have recently emerged as a promising system for low-cost and large-scale production of therapeutic proteins. Despite many advantages plants offer as hosts for expression of recombinant proteins, there are certain limitations caused by major structural differences between plant and...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01000691068/Details |
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| Matična publikacija: |
Food technology and biotechnology 45 (2007), 1 ; str. 1-10 |
| Glavni autor: | Balen, Biljana (-) |
| Ostali autori: | Krsnik-Rasol, Marijana (-) |
| Vrsta građe: | Članak |
| Jezik: | eng |
| Predmet: | |
| Online pristup: |
Digitalni arhiv mrežnih publikacija |
| LEADER | 01620caa a2200289 ir4500 | ||
|---|---|---|---|
| 001 | NSK01000691068 | ||
| 003 | HR-ZaNSK | ||
| 005 | 20130425124544.0 | ||
| 007 | ta | ||
| 008 | 090219s2007 ci ||| ||eng | ||
| 035 | |9 (HR-ZaNSK)693531 | ||
| 035 | |a (HR-ZaNSK)000691068 | ||
| 040 | |a HR-ZaNSK |b hrv |c HR-ZaNSK |e ppiak | ||
| 042 | |a croatica | ||
| 080 | |a 57 |2 MRF 1998. | ||
| 080 | |a 58 |2 MRF 1998. | ||
| 100 | 1 | |a Balen, Biljana | |
| 245 | 1 | 0 | |a N-glycosylation of recombinant therapeutic glycoproteins in plant systems / |c Biljana Balen and Marijana Krsnik-Rasol. |
| 300 | |b Ilustr. | ||
| 504 | |a Bibliografija: 78 jed | ||
| 520 | |a Transgenic plants have recently emerged as a promising system for low-cost and large-scale production of therapeutic proteins. Despite many advantages plants offer as hosts for expression of recombinant proteins, there are certain limitations caused by major structural differences between plant and mammalian N-linked glycans. Thus, efforts are being made in order to eliminate, or at least minimize, plant-specific N-glycosylation as well as to supplement the plant endogenous system with human glycosyltransferases to obtain »humanized« non-immunogenic N-glycans on plant-made pharmaceuticals aimed for human therapy | ||
| 653 | |a Biljke |a Ishrana |a Genetička istraživanja | ||
| 700 | 1 | |a Krsnik-Rasol, Marijana | |
| 773 | 0 | |t Food technology and biotechnology |x 1330-9862 |g 45 (2007), 1 ; str. 1-10 |w nsk.(HR-ZaNSK)000174173 | |
| 981 | |b B11/07 | ||
| 998 | |a rado0902 |c rpeo111228 | ||
| 856 | 4 | 2 | |u http://damp.nsk.hr/index.php?show=archive&idpublication=401 |y Digitalni arhiv mrežnih publikacija |