Novel expression patterns for trefoil peptides
Summary: Trefoil peptides: Tff1, Tff2 and Tff3, assigned to the so-called trefoil factor family (TFF), are secretory proteins predominantly expressed by the gastrointestinal (GI) epithelial cells. Their multiple protective functions include an important role in immune response and apoptosis. Here, a...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01000710105/Details |
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| Matična publikacija: |
Croatica chemica acta 81 (2008), 1 ; str. 113-117 |
| Glavni autor: | Lubka, Maria (-) |
| Ostali autori: | Pusch, Carsten M. (-), Blin, Nikolaus, Baus Lončar, Mirela |
| Vrsta građe: | Članak |
| Jezik: | eng |
| Predmet: | |
| Online pristup: |
CROATICA CHEMICA ACTA |
| LEADER | 02095caa a2200349 ir4500 | ||
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| 001 | NSK01000710105 | ||
| 003 | HR-ZaNSK | ||
| 005 | 20120313094707.0 | ||
| 007 | ta | ||
| 008 | 090820s2008 ci ||| ||eng | ||
| 035 | |9 (HR-ZaNSK)712654 | ||
| 035 | |a (HR-ZaNSK)000710105 | ||
| 040 | |a HR-ZaNSK |b hrv |c HR-ZaNSK |e ppiak | ||
| 041 | 0 | |a eng |b hrv | |
| 042 | |a croatica | ||
| 080 | |a 57 |2 MRF 1998. | ||
| 080 | |a 59 |2 MRF 1998. | ||
| 080 | |a 616 |2 MRF 1998. | ||
| 100 | 1 | |a Lubka, Maria | |
| 245 | 1 | 0 | |a Novel expression patterns for trefoil peptides : |b presence of Tff2 and Tff3 in rodent cochlea / |c Maria Lubka, Carsten M. Pusch, Nikolaus Blin and Mirela Baus-Lončar. |
| 300 | |b Ilustr. | ||
| 504 | |a Bibliografija: 34 jed | ||
| 504 | |a Sažetak | ||
| 520 | 8 | |a Summary: Trefoil peptides: Tff1, Tff2 and Tff3, assigned to the so-called trefoil factor family (TFF), are secretory proteins predominantly expressed by the gastrointestinal (GI) epithelial cells. Their multiple protective functions include an important role in immune response and apoptosis. Here, a novel localization of Tff2 and Tff3 in the cochlea of mouse inner ear is presented. Tffs expression and localization in mouse cochlea was analyzed by using the quantitative real time PCR (qPCR) and immunohistochemistry. Tff2 and Tff3 mRNA quantification by qPCR showed their presence in the cochlea. Immunohistochemistry demonstrated the presence of Tff2 in the spiral ligament and limbus and for Tff3 in the spiral ligament and the organ of Corti. These new and surprising findings of Tff's presence in the cochlea indicate a new role of TFFs connected with the organ of hearing which still needs to be physiologically evaluated | |
| 653 | |a Trefiol proteini |a Unutrašnje uho |a Pužnica |a Imunohistokemija | ||
| 700 | 1 | |a Pusch, Carsten M. | |
| 700 | 1 | |a Blin, Nikolaus | |
| 700 | 1 | |a Baus Lončar, Mirela | |
| 773 | 0 | |t Croatica chemica acta |x 0011-1643 |g 81 (2008), 1 ; str. 113-117 |w nsk.(HR-ZaNSK)000001621 | |
| 981 | |b B02/08 |p CRO | ||
| 998 | |a rado090820 |c mzoo120313 | ||
| 856 | 4 | 2 | |u http://public.carnet.hr/ccacaa/ |y CROATICA CHEMICA ACTA |