TNF-α, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease
Summary: COPD (chronic obstructive pulmonary disease) is a chronic progressive inflammatory disease characterised by limitations in lung airflow that is not fully reversible. The concentrations and correlations of TNF-α, CXCL8, big ET-1 and hsCRP were investigated in healthy non-smokers, healthy smo...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01000710163/Details |
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| Matična publikacija: |
Croatica chemica acta 81 (2008), 1 ; str. 211-217 |
| Glavni autor: | Marević, Sanja (-) |
| Ostali autori: | Petrik, Jozsef (-), Vrkić, Nada, Popović-Grle, Sanja, Žanić-Grubišić, Tihana, Čepelak, Ivana |
| Vrsta građe: | Članak |
| Jezik: | eng |
| Predmet: | |
| Online pristup: |
CROATICA CHEMICA ACTA |
| LEADER | 02419caa a2200385 ir4500 | ||
|---|---|---|---|
| 001 | NSK01000710163 | ||
| 003 | HR-ZaNSK | ||
| 005 | 20151203111426.0 | ||
| 007 | ta | ||
| 008 | 090820s2008 ci ||| ||eng | ||
| 035 | |9 (HR-ZaNSK)712713 | ||
| 035 | |a (HR-ZaNSK)000710163 | ||
| 040 | |a HR-ZaNSK |b hrv |c HR-ZaNSK |e ppiak | ||
| 041 | 0 | |a eng |b hrv | |
| 042 | |a croatica | ||
| 080 | |a 57 |2 MRF 1998. | ||
| 080 | |a 54 |2 MRF 1998. | ||
| 080 | |a 616 |2 MRF 1998. | ||
| 100 | 1 | |a Marević, Sanja | |
| 245 | 1 | 0 | |a TNF-α, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease / |c Sanja Marević, Jozsef Petrik, Nada Vrkić, Sanja Popović-Grle, Tihana Žanić-Grubišić and Ivana Čepelak. |
| 246 | 3 | |a Tumor Necrosis Factor-Alpha | |
| 300 | |b Ilustr. | ||
| 504 | |a Bibliografija: 37 jed | ||
| 504 | |a Sažetak | ||
| 520 | 8 | |a Summary: COPD (chronic obstructive pulmonary disease) is a chronic progressive inflammatory disease characterised by limitations in lung airflow that is not fully reversible. The concentrations and correlations of TNF-α, CXCL8, big ET-1 and hsCRP were investigated in healthy non-smokers, healthy smokers and patients with COPD in order to study their possible role in the pathophysiology of COPD. The concentrations of TNF-α, CXCL8 and big ET-1 were not statistically different between the experimental groups. No significant differences for the measured analytes were found between smokers and the non-smokers in the control group. The Spearman coefficient of correlation between the concentrations of TNF-α and CXCL8 was r = 0.638 (p<0.0001). However, the concentration of hsCRP was significantly higher in patients with COPD than in the control group (p = 0.0004). hsCRP proved to be a more sensitive diagnostic parameter than TNF-α, CXCL8 and big ET-1 in the systemic circulation in patients with COPD | |
| 653 | |a Kronična opstruktivna plućna bolest |a Čimbenik tumorske nekroze alfa |a TNF-α |a Interleukin-8 |a Veliki endotelin-1 |a Visoko osjetljivi C-reaktivni protein | ||
| 700 | 1 | |a Petrik, Jozsef | |
| 700 | 1 | |a Vrkić, Nada | |
| 700 | 1 | |a Popović-Grle, Sanja | |
| 700 | 1 | |a Žanić-Grubišić, Tihana | |
| 700 | 1 | |a Čepelak, Ivana | |
| 773 | 0 | |t Croatica chemica acta |x 0011-1643 |g 81 (2008), 1 ; str. 211-217 |w nsk.(HR-ZaNSK)000001621 | |
| 981 | |b B02/08 |p CRO | ||
| 998 | |a rado090820 |c mzoo120314 | ||
| 856 | 4 | 2 | |u http://public.carnet.hr/ccacaa/ |y CROATICA CHEMICA ACTA |