Expression of MAGE-A1, MAGE-A3/4 and NY-ESO-1 cancer-testis antigens in fetal testis
Summary: Immunohistochemical expression of MAGE-A1, MAGE-A3/4 and NY-ESO-1/LAGE-1 cancer testis antigens (CTA) was assessed in 24 fetal testes from 15th to 36th week of gestation. Three monoclonal antibodies were used for immunohistochemical staining: 77B recognizing MAGE-A1, 57B recognizing multipl...
Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01000733960/Details |
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Matična publikacija: |
Acta dermatovenerologica Croatica 17 (2009), 2 ; str. 103-107 |
Glavni autor: | Hudolin, Tvrtko (-) |
Ostali autori: | Kaštelan, Željko (-), Derežić, Daniel, Bašić-Jukić, Nikolina, Spagnoli, Giulio C., Juretić, Antonio, Ježek, Davor |
Vrsta građe: | Članak |
Jezik: | eng |
Predmet: | |
Online pristup: |
Acta Dermatovenerologica Croatica |
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005 | 20121011093309.0 | ||
007 | ta | ||
008 | 100420s2009 ci ||| ||eng | ||
035 | |9 (HR-ZaNSK)736582 | ||
035 | |a (HR-ZaNSK)000733960 | ||
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042 | |a croatica | ||
080 | |a 57 |2 MRF 1998. | ||
080 | |a 616 |2 MRF 1998. | ||
100 | 1 | |a Hudolin, Tvrtko | |
245 | 1 | 0 | |a Expression of MAGE-A1, MAGE-A3/4 and NY-ESO-1 cancer-testis antigens in fetal testis / |c Tvrtko Hudolin, Željko Kaštelan, Danijel Derežić, Nikolina Bašić-Jukić, Giulio Cesare Spagnoli, Antonio Juretić, Davor Ježek. |
300 | |b Ilustr. | ||
504 | |a Bibliografija: 11 jed | ||
520 | 8 | |a Summary: Immunohistochemical expression of MAGE-A1, MAGE-A3/4 and NY-ESO-1/LAGE-1 cancer testis antigens (CTA) was assessed in 24 fetal testes from 15th to 36th week of gestation. Three monoclonal antibodies were used for immunohistochemical staining: 77B recognizing MAGE-A1, 57B recognizing multiple MAGE-A CTA, and D8.38 recognizing NY-ESO-1/ LAGE-1. Expression of MAGE-A1 was not observed in fetal testis samples, whereas multi-MAGE-A and NY-ESO-1/LAGE-1 specific reagents stained pro-spermatogonia in all samples with different expression levels during the period of fetal development observed. Significant expression of MAGEA3/ 4 and almost continuous expression of NY-ESO-1 in fetal testes after 22nd week of gestation suggested their important role in the development of sex cords and pro-spermatogonia in particular | |
653 | 0 | |a MAGE-A |a NY-ESO-1 |a Antigen |a Rak testisa | |
700 | 1 | |a Kaštelan, Željko | |
700 | 1 | |a Derežić, Daniel | |
700 | 1 | |a Bašić-Jukić, Nikolina | |
700 | 1 | |a Spagnoli, Giulio C. | |
700 | 1 | |a Juretić, Antonio | |
700 | 1 | |a Ježek, Davor | |
773 | 0 | |t Acta dermatovenerologica Croatica |x 1330-027X |g 17 (2009), 2 ; str. 103-107 |w nsk.(HR-ZaNSK)000009221 | |
981 | |b B02/09 | ||
998 | |a Luko100420 |c vol2o121011 | ||
856 | 4 | 2 | |u http://adc.mef.hr/index.php |y Acta Dermatovenerologica Croatica |