Synthesis, structure and cytotoxicity of platinum(IV) complexes of 3-aminocyclohexanespiro-5-hydantoin and 3-aminocycloheptanespiro-5-hydantoin
Summary: Two new platinum(IV) complexes of 3-aminocyclohexanespiro-5-hydantoin (achsh) and 3-aminocycloheptanespiro-5-hydantoin (achpsh) were prepared and characterized. Ab initio calculation of the structure and the measurements of IR and NMR spectra of complexes were also performed. The complexes...
Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01000734843/Details |
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Matična publikacija: |
Croatica chemica acta 82 (2009), 3 ; str. 607-612 |
Glavni autor: | Kushev, Daniel (-) |
Ostali autori: | Enčev, Venelin (-), Najdenova, Emilija Dimitrova, Detcheva, Roumiana, Spassovska, Nadejda, Grancharov, Konstantin |
Vrsta građe: | Članak |
Jezik: | eng |
Predmet: | |
Online pristup: |
Croatica Chemica Acta |
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035 | |a (HR-ZaNSK)000734843 | ||
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042 | |a croatica | ||
080 | |a 54 |2 MRF 1998. | ||
100 | 1 | |a Kushev, Daniel | |
245 | 1 | 0 | |a Synthesis, structure and cytotoxicity of platinum(IV) complexes of 3-aminocyclohexanespiro-5-hydantoin and 3-aminocycloheptanespiro-5-hydantoin / |c Daniel Kushev, Venelin Enchev, Emilya Naydenova, Roumiana Detcheva, Nadejda Spassovska, and Konstantin Grancharov. |
300 | |b Ilustr. | ||
504 | |a Bibliografija: 24 jed | ||
520 | 8 | |a Summary: Two new platinum(IV) complexes of 3-aminocyclohexanespiro-5-hydantoin (achsh) and 3-aminocycloheptanespiro-5-hydantoin (achpsh) were prepared and characterized. Ab initio calculation of the structure and the measurements of IR and NMR spectra of complexes were also performed. The complexes were evaluated for in vitro cytotoxicity in murine erythroleukemia (MEL) cells, clone F4N. The complexes exerted low in vitro toxicity, comparable with that of the corresponding platinum(II) complexes | |
653 | 0 | |a Platina(IV) |a Citotoksičnost |a Molekularna struktura | |
700 | 1 | |a Enčev, Venelin | |
700 | 1 | |a Najdenova, Emilija Dimitrova | |
700 | 1 | |a Detcheva, Roumiana | |
700 | 1 | |a Spassovska, Nadejda | |
700 | 1 | |a Grancharov, Konstantin | |
773 | 0 | |t Croatica chemica acta |x 0011-1643 |g 82 (2009), 3 ; str. 607-612 |w nsk.(HR-ZaNSK)000001621 | |
981 | |b B02/09 | ||
998 | |a Luko100427 |c vol2o130307 | ||
856 | 4 | 2 | |u http://hrcak.srce.hr/cca |y Croatica Chemica Acta |