Acute phase proteins in psoriasis
Abstract: Psoriasis is a chronic, relapsing, inflammatory and hyperproliferative skin disorder. The levels of acute phase proteins are suggested to be elevated in those patients with acute disease. The expression of selected acute phase proteins as the parameters of humoral immunity has been analyze...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01000734872/Details |
|---|---|
| Matična publikacija: |
Collegium antropologicum 33 (2009), 1 ; str. 83-86 |
| Glavni autor: | Biljan, Darko (-) |
| Ostali autori: | Šitum, Mirna (-), Kostović, Krešimir, Batinac, Tanja, Matišić, Danica |
| Vrsta građe: | Članak |
| Jezik: | eng |
| Predmet: | |
| Online pristup: |
Collegium Antropologicum |
| LEADER | 02233caa a2200337 ir4500 | ||
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| 001 | NSK01000734872 | ||
| 003 | HR-ZaNSK | ||
| 005 | 20130423094854.0 | ||
| 007 | ta | ||
| 008 | 100427s2009 ci ||| ||eng | ||
| 035 | |9 (HR-ZaNSK)737494 | ||
| 035 | |a (HR-ZaNSK)000734872 | ||
| 040 | |a HR-ZaNSK |b hrv |c HR-ZaNSK |e ppiak | ||
| 041 | 0 | |a eng |b hrv | |
| 042 | |a croatica | ||
| 080 | |a 616 |2 MRF 1998. | ||
| 100 | 1 | |a Biljan, Darko | |
| 245 | 1 | 0 | |a Acute phase proteins in psoriasis / |c Darko Biljan, Mirna Šitum, Krešimir Kostović, Tanja Batinac and Danica Matišić. |
| 300 | |b Ilustr. | ||
| 504 | |a Bibliografija: 15 jed | ||
| 504 | |a Sažetak | ||
| 520 | 8 | |a Abstract: Psoriasis is a chronic, relapsing, inflammatory and hyperproliferative skin disorder. The levels of acute phase proteins are suggested to be elevated in those patients with acute disease. The expression of selected acute phase proteins as the parameters of humoral immunity has been analyzed in 70 patients with acute psoriasis and 40 healthy controls. The aim was to evaluate the inflammatory response in the exacerbation of psoriasis and to determine the correlation of these objective inflammatory parameters with clinical features of disease activity. Main demographic and epidemiologic features were, as well, analysed. The plasma levels of C-reactive protein (CRP) (c2 = 23.61; p<0.005), and alpha1-acid glycoprotein (a1-AGP) (c2 = 7.,42; p<0.01) were significantly increased in those patients with acute phase of the disease compared to healthy controls. Our results suggest that psoriasis is an inflammatory disease and therefore its worsening seemed to be linked to the increase in the inflammatory response. It seems that CRP and al-AGP levels could serve as important prognostic factors for the worsening of psoriasis | |
| 653 | 0 | |a Psorijaza |a C-reaktivni protein |a Alfa1-kiseli glikoprotein | |
| 700 | 1 | |a Šitum, Mirna | |
| 700 | 1 | |a Kostović, Krešimir | |
| 700 | 1 | |a Batinac, Tanja | |
| 700 | 1 | |a Matišić, Danica | |
| 773 | 0 | |t Collegium antropologicum |x 0350-6134 |g 33 (2009), 1 ; str. 83-86 |w nsk.(HR-ZaNSK)000000360 | |
| 981 | |b B02/09 |p CRO | ||
| 998 | |a rado100427 |c vol2o130423 | ||
| 856 | 4 | 2 | |u http://hrcak.srce.hr/coll-antropol |y Collegium Antropologicum |