Efficacy and safety of budesonide/formeterol combination therapy in asthma patients
Abstract: Budesonide/formoterol as single inhaler was developed for treating asthma patients who are not adequately controlled on glucocorticoides alone. The aim of this study was to evaluate efficacy, safety and patient/physician satisfaction of budesonide/formoterol therapy.Total of 268 asthma pat...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01000737359/Details |
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| Matična publikacija: |
Collegium antropologicum 33 (2009), 2 ; str. 587-591 |
| Glavni autor: | Jakopović, Marko (-) |
| Ostali autori: | Pavičić, Fadila (-), Redžepi, Gzim, Pleština, Sanja, Janković, Mateja, Šamija, Mirko, Samaržija, Miroslav |
| Vrsta građe: | Članak |
| Jezik: | eng |
| Predmet: | |
| Online pristup: |
Collegium Antropologicum |
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| 100 | 1 | |a Jakopović, Marko | |
| 245 | 1 | 0 | |a Efficacy and safety of budesonide/formeterol combination therapy in asthma patients / |c Marko Jakopović, Fadila Pavičić, Gzim Redžepi, Sanja Pleština, Mateja Janković, Mirko Šamija and Miroslav Samaržija. |
| 300 | |b Ilustr. | ||
| 504 | |a Bibliografija: | ||
| 504 | |a Sažetak | ||
| 520 | 8 | |a Abstract: Budesonide/formoterol as single inhaler was developed for treating asthma patients who are not adequately controlled on glucocorticoides alone. The aim of this study was to evaluate efficacy, safety and patient/physician satisfaction of budesonide/formoterol therapy.Total of 268 asthma patients (120 men, mean age 38,8 ± 37,2 years, and 148 women, mean age 42,2 ± 32 years) were included in the study. All patients received budesonide/formoterol bid (640 mcg of budesonide and 18 mcg of formoterol daily) during run-in period for three weeks. Patients were followed during 14 weeks at 5 visits.At each visit lung function (FEV1 and PEF) was measured,presence of side affects was recorded and questionnaire was given to patients and physicians to estimate the level of satisfaction with budesonide/formoterol therapy (1 very unsatisfied to 5 very satisfied). Significant improvement was noticed in FEV1, from 76,25% of predicted value to 86,94% (p<0,01); and in PEF from 380,84 L/min to 442,29 L/min (p<0,01) in all patients. At the end of the study patients’ satisfaction with budesonide/formeterol therapy was significantly improved comparing with satisfaction with previously taken therapy,in average grade, from 2,94 to 4,56 (p<0,01),and similar results were noticed with physicians’ satisfaction, from 2,60 to 4,41 (p<0,01). Budesonide/formoterol in single inhaler, significantly improved lung function in patients with asthma | |
| 653 | 0 | |a Budezonid |a Formoterol |a Astma | |
| 700 | 1 | |a Pavičić, Fadila | |
| 700 | 1 | |a Redžepi, Gzim | |
| 700 | 1 | |a Pleština, Sanja | |
| 700 | 1 | |a Janković, Mateja | |
| 700 | 1 | |a Šamija, Mirko | |
| 700 | 1 | |a Samaržija, Miroslav | |
| 773 | 0 | |t Collegium antropologicum |x 0350-6134 |g 33 (2009), 2 ; str. 587-591 |w nsk.(HR-ZaNSK)000000360 | |
| 981 | |b B04/09 |p CRO | ||
| 998 | |a rado100524 |c vol2o130418 | ||
| 856 | 4 | 2 | |u http://hrcak.srce.hr/coll-antropol |y Collegium Antropologicum |