Effect of botulinum toxin-A injection on intraocular pressure and proptosis in thyroid associated orbitopathy
Abstract: The aim of this study was to evaluate the effects of extraocular muscle injection of botulinum toxin-A (BTX-A) on intraocular pressure (IOP) and proptosis in patients with ocular motility disturbances in thyroid associated orbitopathy (TAO). In 17 patients (20 eyes) with restrictive strabi...
Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01000737975/Details |
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Matična publikacija: |
Collegium antropologicum 33 (2009), 4 ; str. 1155-1157 |
Glavni autor: | Lešin, Mladen (-) |
Ostali autori: | Bojić, Lovre (-), Romac, Rinaldo, Lešin, Joško, Ivanišević, Milan, liječnik, Galetović, Davor, Rogošić, Veljko, liječnik |
Vrsta građe: | Članak |
Jezik: | eng |
Predmet: | |
Online pristup: |
Collegium Antropologicum |
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100 | 1 | |a Lešin, Mladen | |
245 | 1 | 0 | |a Effect of botulinum toxin-A injection on intraocular pressure and proptosis in thyroid associated orbitopathy / |c Mladen Lešin, Lovro Bojić, Rinaldo Romac, Joško Lešin, Milan Ivanišević, Davor Galetović and Veljko Rogošić. |
300 | |b Ilustr. | ||
504 | |a Bibliografija: 16 jed | ||
504 | |a Sažetak | ||
520 | 8 | |a Abstract: The aim of this study was to evaluate the effects of extraocular muscle injection of botulinum toxin-A (BTX-A) on intraocular pressure (IOP) and proptosis in patients with ocular motility disturbances in thyroid associated orbitopathy (TAO). In 17 patients (20 eyes) with restrictive strabismus and diplopia, BTX -A injections were applied. Intraocular pressure was measured with a Goldmann applanation tonometer in primary gaze position before and 2–4 weeks after BTX-A injection. Extraorbital prominention of the eyeball was measured before and after BTX -A injection using a Hertel instrument. Before the injection, the mean IOP in primary position of gaze was 18.6± 2.8 mmHg and 2–4 weeks after BTX-A injection was 16.9±3.3 mmH; (p=0.001). There was no statistically significant difference in Hertel egzophthalmometer readings before and after BTX-A injection, 21.5±2.7 mm vs 22.0± 2.6 mm; (p=0.678). In conclusion, BTX-A injection has a secondary lowering effect on IOP in TAO due to relaxation of extraocular muscles, but with no influence on proptosis | |
653 | 0 | |a Botulinski toksin tip A |a Strabizam |a Očni mišići |a Intraokularni tlak |a Proptoza |a Tiroidna orbitopatija | |
700 | 1 | |a Bojić, Lovre | |
700 | 1 | |a Romac, Rinaldo | |
700 | 1 | |a Lešin, Joško | |
700 | 1 | |a Ivanišević, Milan, |c liječnik | |
700 | 1 | |a Galetović, Davor | |
700 | 1 | |a Rogošić, Veljko, |c liječnik | |
773 | 0 | |t Collegium antropologicum |x 0350-6134 |g 33 (2009), 4 ; str. 1155-1157 |w nsk.(HR-ZaNSK)000000360 | |
981 | |b B04/09 |p CRO | ||
998 | |a rado100528 |c vol2o130528 | ||
856 | 4 | 2 | |u http://hrcak.srce.hr/coll-antropol |y Collegium Antropologicum |