Effect of botulinum toxin-A injection on intraocular pressure and proptosis in thyroid associated orbitopathy

Abstract: The aim of this study was to evaluate the effects of extraocular muscle injection of botulinum toxin-A (BTX-A) on intraocular pressure (IOP) and proptosis in patients with ocular motility disturbances in thyroid associated orbitopathy (TAO). In 17 patients (20 eyes) with restrictive strabi...

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Permalink: http://skupni.nsk.hr/Record/nsk.NSK01000737975/Details
Matična publikacija: Collegium antropologicum
33 (2009), 4 ; str. 1155-1157
Glavni autor: Lešin, Mladen (-)
Ostali autori: Bojić, Lovre (-), Romac, Rinaldo, Lešin, Joško, Ivanišević, Milan, liječnik, Galetović, Davor, Rogošić, Veljko, liječnik
Vrsta građe: Članak
Jezik: eng
Predmet:
Online pristup: Collegium Antropologicum
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100 1 |a Lešin, Mladen 
245 1 0 |a Effect of botulinum toxin-A injection on intraocular pressure and proptosis in thyroid associated orbitopathy /  |c Mladen Lešin, Lovro Bojić, Rinaldo Romac, Joško Lešin, Milan Ivanišević, Davor Galetović and Veljko Rogošić. 
300 |b Ilustr. 
504 |a Bibliografija: 16 jed 
504 |a Sažetak 
520 8 |a Abstract: The aim of this study was to evaluate the effects of extraocular muscle injection of botulinum toxin-A (BTX-A) on intraocular pressure (IOP) and proptosis in patients with ocular motility disturbances in thyroid associated orbitopathy (TAO). In 17 patients (20 eyes) with restrictive strabismus and diplopia, BTX -A injections were applied. Intraocular pressure was measured with a Goldmann applanation tonometer in primary gaze position before and 2–4 weeks after BTX-A injection. Extraorbital prominention of the eyeball was measured before and after BTX -A injection using a Hertel instrument. Before the injection, the mean IOP in primary position of gaze was 18.6± 2.8 mmHg and 2–4 weeks after BTX-A injection was 16.9±3.3 mmH; (p=0.001). There was no statistically significant difference in Hertel egzophthalmometer readings before and after BTX-A injection, 21.5±2.7 mm vs 22.0± 2.6 mm; (p=0.678). In conclusion, BTX-A injection has a secondary lowering effect on IOP in TAO due to relaxation of extraocular muscles, but with no influence on proptosis 
653 0 |a Botulinski toksin tip A  |a Strabizam  |a Očni mišići  |a Intraokularni tlak  |a Proptoza  |a Tiroidna orbitopatija 
700 1 |a Bojić, Lovre 
700 1 |a Romac, Rinaldo 
700 1 |a Lešin, Joško 
700 1 |a Ivanišević, Milan,  |c liječnik 
700 1 |a Galetović, Davor 
700 1 |a Rogošić, Veljko,  |c liječnik 
773 0 |t Collegium antropologicum  |x 0350-6134  |g 33 (2009), 4 ; str. 1155-1157  |w nsk.(HR-ZaNSK)000000360 
981 |b B04/09  |p CRO 
998 |a rado100528  |c vol2o130528 
856 4 2 |u http://hrcak.srce.hr/coll-antropol  |y Collegium Antropologicum