The comorbidity of diabetes mellitus and psychiatric disorders

Diabetes mellitus is a chronic disease affecting approximately 6% of the general population. Depression and schizophrenia are often comorbid with diabetes. There are two main ways to explain this phenomenon. Firstly, patients with diabetes mellitus have higher incidence of psychiatric disorders and...

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Permalink: http://skupni.nsk.hr/Record/nsk.NSK01000744291/Details
Matična publikacija: Psychiatria Danubina
21 (2009), 4 ; str. 585-588
Glavni autor: Medved, Vesna (-)
Ostali autori: Jovanović, Nikolina, liječnica (-), Popović-Knapić, Vesna
Vrsta građe: Članak
Jezik: eng
Predmet:
Online pristup: http://hrcak.srce.hr/psychiatria-danubina
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245 1 4 |a The comorbidity of diabetes mellitus and psychiatric disorders /  |c Vesna Medved, Nikolina Jovanović & V. [Vesna] Popović Knapić. 
500 |a 4th Croatian congress on psychopharmacotherapy with international participation, Zadar, October 7-10, 2009 
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520 |a Diabetes mellitus is a chronic disease affecting approximately 6% of the general population. Depression and schizophrenia are often comorbid with diabetes. There are two main ways to explain this phenomenon. Firstly, patients with diabetes mellitus have higher incidence of psychiatric disorders and secondly, antidepressants and antipsychotics may cause metabolic abnormalities. Antidepressants with noradrenergic activity have the highest potential to cause metabolic abnormalities. In schizophrenia, the risk is highest with clozapine and olanzapine pose the highest risk, moderate for risperidone and quetiapine, while ziprasidone and sertindole have not been associated with diabetes. During the first three months, weight gain should be monitored on monthly basis, while biochemical analysis should be performed after the first three months, and then once a year. In patients with significant weight gain, increase of blood glucose level or dyslipidemia, the first intervention should be switch to another antipsychotic. If necessary, a patient should be referred to an endocrinologist and advised on changing their life style 
653 0 |a Komorbiditet  |a Dijabetes  |a Depresija  |a Shizofrenija  |a Antidepresivi 
700 1 |a Jovanović, Nikolina,  |c liječnica 
700 1 |a Popović-Knapić, Vesna 
773 0 |t Psychiatria Danubina  |x 0353-5053  |g 21 (2009), 4 ; str. 585-588 
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