Gut microbiota and body weight
The link between gut microbiota and insulin resistance has an important clinical impact, people affected by dysbiosis having a predisposition for developing: obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, cancers, cardiovascular, neurodegenerative and psychiatric diseases. Dysb...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01001024835/Details |
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| Matična publikacija: |
Psihologijske teme (Online) 27 (2018), 1 ; str. 33-53 |
| Glavni autori: | Duca, Ioana (Author), Rusu, Flaviu, Chira, Alexandra, Dumitrescu, Dan Lucian |
| Vrsta građe: | e-članak |
| Jezik: | eng |
| Predmet: | |
| Online pristup: |
https://doi.org/10.31820/pt.27.1.3 Elektronička verzija članka Elektronička verzija članka |
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| 007 | cr|||||||||||| | ||
| 008 | 190321s2018 ci | |0|| ||eng | ||
| 024 | 7 | |2 doi |a 10.31820/pt.27.1.3 | |
| 035 | |a (HR-ZaNSK)001024835 | ||
| 040 | |a HR-ZaNSK |b hrv |c HR-ZaNSK |e ppiak | ||
| 041 | 0 | |a eng |b spa | |
| 042 | |a croatica | ||
| 044 | |a ci |c hr | ||
| 080 | 1 | |a 616 |2 2011 | |
| 100 | 1 | |a Duca, Ioana |4 aut |9 HR-ZaNSK | |
| 245 | 1 | 0 | |a Gut microbiota and body weight |h [Elektronička građa] : |b a review / |c Ioana Duca, Flaviu Rusu, Alexandra Chira, Dan Lucian Dumitrescu. |
| 300 | |b Ilustr. | ||
| 504 | |a Bibliografija: str. 46-52. | ||
| 504 | |a Resumen | ||
| 520 | |a The link between gut microbiota and insulin resistance has an important clinical impact, people affected by dysbiosis having a predisposition for developing: obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, cancers, cardiovascular, neurodegenerative and psychiatric diseases. Dysbiosis may lead through chronic inflammation to obesity and metabolic syndrome. We carried out a systematic review of the studies dedicated to the role of gut microbiota in weight gain and obesity. A systematic literature search of recent data published in electronic databases, was performed, using as search phrase: "gut microbiome and body weight and obesity". Studies that contained no data about the influence of gut microbiota changes on obesity were excluded. Western diet, antibiotic use in childhood, excessive maternal pre-pregnancy weight, Cesarean delivery, and testosterone deficiency are triggers of the alteration of microbiota and subsequently the appearance of obesity. Predominance of Firmicutes and anaerobic genera, changes in the mycobiome and viral intestinal population are implied in the etiology of obesity. Prebiotics, polyphenols, different herbs, medication (antidiabetics, calcium), physical exercise, rich fibre intake and bariatric surgery are the most important therapeutic options. Personalized dietary treatments, antiviral agents and mycobiome manipulation would represent the new target in treating obesity. Any change of the quantitative and qualitative composition of microbiota has influence on the components of metabolic syndrome, so any management strategy for the treatment or prevention of obesity in children and adulthood should have the microbiome as target. | ||
| 520 | |a La relación entre la microbioma intestinal y la resistencia a la insulina tiene un impacto clínico importante dado que la gente afectada por disbiosis tiene predisposiciones para desarrollar la obesidad, la diabetes mellitus tipo 2, la enfermedad de hígado graso no alcohólico, cánceres, enfermedades cardiovasculares, neurodegenerativas y psiquiátricas. La disbiosis puede convertirse en una inflamación crónica, obesidad o síndrome metabólico. Hemos hecho una revisión sistemática de los estudios dedicados al papel de la microbioma intestinal para el aumento de peso y la obesidad. Una búsqueda sistemática de datos recientes publicados en las bases de datos electrónicas se ha llevado a cabo usando la frase “gut microbiome and body weight and obesity”. Se ha excluido a los estudios que no contenían informaciones sobre la influencia de los cambios de la microbioma intestinal en la obesidad. La dieta occidental, uso de los antibióticos en la niñez, peso excesivo antes del embarazo, parto por cesárea y deficiencia de testosterona provocan la alteración de la microbioma y por consiguiente la apariencia de la obesidad. El predominio de firmicutes y géneros anaeróbicos, cambios en el microbioma y populación intestinal viral están implícitos en la etiología de la obesidad. Prebióticos, polifenoles, diferentes hierbas, medicamentos (antidiabéticos, calcio), ejercicio físico, consumo de fibras y cirugía bariátrica son las opciones terapéuticas más importantes. Tratamientos dietéticos personalizados, agentes antivirales y manipulación de la microbioma representarían nuevas metas en el tratamiento de la obesidad. Cada cambio en la composición cuantitativa o cualitativa de la microbioma influye en los componentes del síndrome metabólico, así que todas las estrategias para el tratamiento o prevención de la obesidad en niños o adultos deberían tener microbioma como su meta. | ||
| 653 | 0 | |a Dijabetes |a Metabolizam |a Mikrobiota |a Pretilost | |
| 700 | 1 | |a Rusu, Flaviu |4 aut |9 HR-ZaNSK | |
| 700 | 1 | |a Chira, Alexandra |4 aut |9 HR-ZaNSK | |
| 700 | 1 | |a Dumitrescu, Dan Lucian |4 aut |9 HR-ZaNSK | |
| 773 | 0 | |t Psihologijske teme (Online) |x 1849-0395 |g 27 (2018), 1 ; str. 33-53 |w nsk.(HR-ZaNSK)000848758 | |
| 981 | |b Be2018 |b B01/18 | ||
| 998 | |b dalo1904 | ||
| 856 | 4 | 0 | |u https://doi.org/10.31820/pt.27.1.3 |
| 856 | 4 | 0 | |u https://hrcak.srce.hr/200011 |y Elektronička verzija članka |
| 856 | 4 | 1 | |y Digitalna.nsk.hr |
| 856 | 4 | 0 | |u http://pt.ffri.hr/index.php/pt/article/view/454 |y Elektronička verzija članka |