The acetylcholine therapy in the treatment of schizophrenia

In the first half of the 20th century, in most European countries, it was thought that cholinesterase and other drugs that counteract acetylcholine should reduce the manifestations of schizophrenia. In 1937, Fiamberti (1894–1970) introduced the transorbital method of lobotomy which established the u...

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Permalink: http://skupni.nsk.hr/Record/nsk.NSK01001059613/Details
Matična publikacija: Acta medico-historica Adriatica (Online)
17 (2019), 1 ; str. 91-102
Glavni autori: Armocida, Giuseppe (Author), Licata, Marta, Gorini, Ilaria, Ciliberti, Rosagemma
Vrsta građe: e-članak
Jezik: eng
Predmet:
Online pristup: https://doi.org/10.31952/amha.17.1.5
Acta medico-historica Adriatica (Online)
Hrčak
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100 1 |a Armocida, Giuseppe  |4 aut 
245 1 4 |a The acetylcholine therapy in the treatment of schizophrenia  |h [Elektronička građa] :  |b the experience of Mario Fiamberti in the Hospital of Varese (1937) = Terapija acetilholinom u liječenju shizofrenije : iskustvo Marija Fiambertija u bolnici Varese (1937.) /  |c Giuseppe Armocida, Marta Licata, Ilaria Gorini, Rosagemma Ciliberti. 
246 3 1 |a Terapija acetilholinom u liječenju shizofrenije :  |b iskustvo Marija Fiambertija u bolnici Varese (1937.) 
300 |b Ilustr. 
504 |a Bibliografija: 28 jed. 
504 |a Summary ; Sažetak. 
520 |a In the first half of the 20th century, in most European countries, it was thought that cholinesterase and other drugs that counteract acetylcholine should reduce the manifestations of schizophrenia. In 1937, Fiamberti (1894–1970) introduced the transorbital method of lobotomy which established the use of acetylcholine shock treatment for curing the disturbances of schizophrenia. Accepting the idea that the psychic alterations of schizophrenia were caused by a pathological interruption of nerve conduction at a presumably cortical level, Fiamberti thought he could apply this to the clinical field using the properties of acetylcholine, an acetic ester of choline. Here, we examined, in detail, the contribution of Mario Fiamberti to acetylcholine therapy. 
520 |a U prvoj polovici 20. stoljeća u većini se europskih zemalja smatralo da bi kolinesteraza i drugi lijekovi koji djeluju protiv acetilkolina trebali smanjiti manifestacije shizofrenije. Godine 1937. Mario Fiamberti (1894. – 1970.) uveo je transorbitalnu metodu lobotomije koja je utvrdila potrebu acetilkolinske šok-terapije u liječenju poremećaja shizofrenije. Prihvaćajući ideju da su psihičke promjene shizofrenije uzrokovane patološkim prekidom živčane provodljivosti na vjerojatno kortikalnoj razini, Fiamberti je mislio da to može primijeniti na kliničkom polju koristeći svojstva acetilkolina, acetilnog ester kolina. U istraživanju je detaljno ispitan doprinos Marija Fiambertija u terapiji acetilkolinom. 
653 0 |a Shizofrenija  |a Acetilkolin terapija  |a Fiambertijeva metoda  |a Povijest medicine 
700 1 |a Licata, Marta  |4 aut 
700 1 |a Gorini, Ilaria  |4 aut 
700 1 |a Ciliberti, Rosagemma  |4 aut 
773 0 |t Acta medico-historica Adriatica (Online)  |x 1334-6253  |g 17 (2019), 1 ; str. 91-102  |w nsk.(HR-ZaNSK)000509064 
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