A paradigmatic case of haemolysis and pseudohyperkalemia in blood gas analysis
A 51-year old male patient was admitted to the hospital with acute dyspnea and history of chronic asthma. Venous blood was drawn into a 3.0 mLheparinized syringe and delivered to the laboratory for blood gas analysis (GEM Premier 4000, Instrumentation Laboratory), which revealed highpotassium value...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01001068973/Details |
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| Matična publikacija: |
Biochemia medica (Online) 29 (2019), 1 ; str. 169-172 |
| Glavni autori: | Salvagno, Gian Luca (Author), Demonte, Davide, Lippi, Giuseppe |
| Vrsta građe: | e-članak |
| Jezik: | eng |
| Predmet: | |
| Online pristup: |
https://doi.org/10.11613/BM.2019.011003 Biochemia medica (Online) Hrčak |
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| 100 | 1 | |a Salvagno, Gian Luca |4 aut | |
| 245 | 1 | 2 | |a A paradigmatic case of haemolysis and pseudohyperkalemia in blood gas analysis |h [Elektronička građa] / |c Gian Luca Salvagno, Davide Demonte, Giuseppe Lippi. |
| 300 | |b Ilustr. | ||
| 504 | |a Bibliografija: 16 jed. | ||
| 504 | |a Abstract. | ||
| 520 | |a A 51-year old male patient was admitted to the hospital with acute dyspnea and history of chronic asthma. Venous blood was drawn into a 3.0 mLheparinized syringe and delivered to the laboratory for blood gas analysis (GEM Premier 4000, Instrumentation Laboratory), which revealed highpotassium value (5.2 mmol/L; reference range on whole blood, 3.5-4.5 mmol/L). This result was unexpected, so that a second venous blood samplewas immediately drawn by direct venipuncture into a 3.5 mL lithium-heparin blood tube, and delivered to the laboratory for repeating potassiumtesting on Cobas 8000 (Roche Diagnostics). The analysis revealed normal plasma potassium (4.6 mmol/L; reference range in plasma, 3.5-5.0 mmol/L)and haemolysis index (5; 0.05 g/L). Due to suspicion of spurious haemolysis, heparinized blood was transferred from syringe into a plastic tube andcentrifuged. Potassium and haemolysis index were then measured in this heparinized plasma, confirming high haemolysis index (50; 0.5 g/L) andpseudohyperkalemia (5.5 mmol/L). Investigation of this case revealed that spurious haemolysis was attributable to syringe delivery in direct ice contactfor ~15 min. This case emphasizes the importance of avoiding sample transportation in ice and the need of developing point of care analysersequipped with interference indices assessment. | ||
| 653 | 0 | |a Kalij |a Hiperkalijemija |a Dijagnostičke pogreške |a Laboratorijska dijagnostika | |
| 700 | 1 | |a Demonte, Davide |4 aut |9 HR-ZaNSK | |
| 700 | 1 | |a Lippi, Giuseppe |4 aut | |
| 773 | 0 | |t Biochemia medica (Online) |x 1846-7482 |g 29 (2019), 1 ; str. 169-172 |w nsk.(HR-ZaNSK)000655372 | |
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| 856 | 4 | 0 | |u https://hrcak.srce.hr/217224 |y Hrčak |