Genetic polymorphism and effect on milk production of CSN2 gene in conventional and local cattle breeds in Croatia
Over the past three decades, the scientific and public interest has been initiated by studies in which the negative effect of milk consumption of beta-casein A1 variant has been observed on consumers" health. The production of "A2 milk" is one of the ways to economically increase the...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01001144836/Details |
|---|---|
| Matična publikacija: |
Mljekarstvo.com 71 (2021), 1 ; str. 3-12 |
| Glavni autori: | Ivanković, Ante, agronom (Author), Pećina, Mateja, Ramljak, Jelena, Pašić, Vedat |
| Vrsta građe: | e-članak |
| Jezik: | eng |
| Predmet: | |
| Online pristup: |
https://doi.org/10.15567/mljekarstvo.2021.0101 Hrčak |
| LEADER | 03599naa a22003854i 4500 | ||
|---|---|---|---|
| 001 | NSK01001144836 | ||
| 003 | HR-ZaNSK | ||
| 005 | 20221031090526.0 | ||
| 006 | m d | ||
| 007 | cr|||||||||||| | ||
| 008 | 220803s2020 ci d |o |0|| ||eng | ||
| 024 | 7 | |2 doi |a 10.15567/mljekarstvo.2021.0101 | |
| 035 | |a (HR-ZaNSK)001144836 | ||
| 040 | |a HR-ZaNSK |b hrv |c HR-ZaNSK |e ppiak | ||
| 041 | 0 | |a eng |b hrv | |
| 042 | |a croatica | ||
| 044 | |a ci |c hr | ||
| 080 | 1 | |a 636/639 |2 2011 | |
| 100 | 1 | |a Ivanković, Ante, |c agronom |4 aut | |
| 245 | 1 | 0 | |a Genetic polymorphism and effect on milk production of CSN2 gene in conventional and local cattle breeds in Croatia |h [Elektronička građa] / |c Ante Ivanković, Mateja Pećina, Jelena Ramljak, Vedat Pašić. |
| 300 | |b Graf. prikazi. | ||
| 504 | |a Bibliografija: 54 jed. | ||
| 504 | |a Abstract ; Sažetak. | ||
| 520 | |a Over the past three decades, the scientific and public interest has been initiated by studies in which the negative effect of milk consumption of beta-casein A1 variant has been observed on consumers" health. The production of "A2 milk" is one of the ways to economically increase the competitiveness of small and medium-sized dairy farms. Breeders of endangered local breeds are also interested in reaffirmation through production of "A2 milk". The aim of this study is to determine frequencies of A1 and A2 variants of beta-casein in three commercial and three local breeds of cattle in Croatia, and their relationship with production indicators of commercial breeds in the first three lactations. The genomic DNA was extracted from hair and determination of CSN2 genotypes was conducted by PCR RFLP method. Data for milk yield and chemical composition were provided by the central database. The dominant presence of A2 variant beta-casein in the investigated cattle breeds (0.650-0.758) and the increase in the frequency of A2 beta-casein in the population of Simmental and Istrian cattle were determined. | ||
| 520 | |a Tijekom protekla tri desetljeća interes znanstvene i ukupne javnosti (potrošača) potaknut je studijama u kojima je zapažen negativan učinak konzumacije mlijeka u kojem je A1 varijanta beta-kazeina na zdravlje potrošača. Proizvodnja "A2 mlijeka" jedan je od načina gospodarskog povećanja kompetitivnosti manjih i srednjih mliječnih farmi. Uzgajivači ugroženih lokalnih pasmina također su zainteresirani za reafirmaciju kroz proizvodnju "A2 mlijeka". Cilj istraživanja je utvrditi frekvencije A1 i A2 varijanti beta-kazeina u konvencionalnim i lokalnim pasminama goveda u Hrvatskoj, te njihovu povezanost s proizvodnim pokazateljima konvencionalnih pasmina u prve tri laktacije. Genomska DNK izolirana korištenjem komercijalnog kita za izolaciju upotrijebljena je za PCR RFLP determinaciju CSN2 genotipova. Podaci o mliječnosti i kemijskom sastavu mlijeka u promatranom uzorku preuzeti su iz središnje baze podataka. Utvrđena je dominantna zastupljenost A2 varijante beta-kazeina u istraženim pasminama goveda (0,650-0,758) te povećanje frekvencije A2 beta-kazeina u populaciji simentalskog i istarskog goveda. | ||
| 653 | 0 | |a Govedo |a Pasmine goveda |a Beta-kazein |a Polimorfizam |a Proizvodnja mlijeka | |
| 700 | 1 | |a Pećina, Mateja |4 aut | |
| 700 | 1 | |a Ramljak, Jelena |4 aut | |
| 700 | 1 | |a Pašić, Vedat |4 aut |9 HR-ZaNSK | |
| 773 | 0 | |t Mljekarstvo.com |x 1846-4025 |g 71 (2021), 1 ; str. 3-12 |w nsk.(HR-ZaNSK)000625306 | |
| 981 | |b Be2020 |b B05/20 | ||
| 998 | |b tino2210 | ||
| 856 | 4 | 0 | |u https://doi.org/10.15567/mljekarstvo.2021.0101 |
| 856 | 4 | 0 | |u https://hrcak.srce.hr/246950 |y Hrčak |
| 856 | 4 | 1 | |y Digitalna.nsk.hr |