Clinical follow-up of canine mast cell tumour cases diagnosed by cytology and histopathology

Canine mast cell tumours (MCT) are malignant neoplasms, and are possibly the most common skin cancers in dogs. A precise diagnosis is fundamental in making appropriate therapeutic decisions and thus avoiding a poor prognosis, which frequently ends in rapid death. In this study, data from 59 dogs dia...

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Permalink: http://skupni.nsk.hr/Record/nsk.NSK01001145238/Details
Matična publikacija: Veterinarska stanica (Online)
52 (2021), 4 ; str. 397-403
Glavni autori: Cifuentes-Arias, Sebastián (Author), Osorio-Morales, Lina, Pedraza-Ordóñez, Francisco
Vrsta građe: e-članak
Jezik: eng
Predmet:
Online pristup: https://doi.org/10.46419/vs.52.4.1
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024 7 |2 doi  |a 10.46419/vs.52.4.1 
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100 1 |a Cifuentes-Arias, Sebastián  |4 aut  |9 HR-ZaNSK 
245 1 0 |a Clinical follow-up of canine mast cell tumour cases diagnosed by cytology and histopathology  |h [Elektronička građa] /  |c Sebastián Cifuentes-Arias, Lina Osorio-Morales, Francisco Pedraza-Ordóñez. 
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504 |a Bibliografija: 21 jed. 
504 |a Abstract ; Sažetak. 
520 |a Canine mast cell tumours (MCT) are malignant neoplasms, and are possibly the most common skin cancers in dogs. A precise diagnosis is fundamental in making appropriate therapeutic decisions and thus avoiding a poor prognosis, which frequently ends in rapid death. In this study, data from 59 dogs diagnosed with mast cell tumours of three malignancy grades were selected and clinical follow-up was carried out over 47 months to determine the relationship between the decision to perform surgery the degree of tumour malignancy and the survival status of the animals. The results showed that the majority of affected animals died as a result of the disease, some of which had undergone surgical treatment. The surviving dogs were diagnosed mostly with mast cell tumours of low malignancy. There was no significant association between surgery and survival. We conclude that cytological analysis is fundamental for an early diagnosis of canine MCTs and enable a more accurate prognosis to guide subsequent treatment. We discuss the need for clear malignancy criteria allowing for adequate cytological classification of these lesions. 
520 |a Mastocitomi u pasa (MCT) maligne su neoplazije te vjerojatno najčešći oblik raka kože u pasa. Precizna dijagnoza ključna je za donošenje ispravnih odluka u svezi liječenja, a tako i za izbjegavanje loših prognoza koje često završavaju brzom smrću. U ovom istraživanju odabrani su podatci 59 pasa kojima je prethodno dijagnosticiran mastocitom tri različita stupnja malignosti te je provedeno kliničko praćenje tijekom 47 mjeseci za ustvrđivanje odnosa između odluke o operaciji, stupnja malignosti tumora i statusa preživljavanja životinja. Rezultati su pokazali da je većina oboljelih životinja, od kojih su neke bile podvrgnute operaciji, uginula uslijed bolesti. Psima koji su preživjeli uglavnom je dijagnosticiran tumor niske malignosti. Nije bilo značajne povezanosti između operacije i preživljavanja. Zaključujemo da je citološka analiza presudna za ranu dijagnozu MCT-a u pasa i za omogućavanje preciznije prognoze koja će voditi daljnje liječenje. Raspravljamo o potrebi uspostave jasnih kriterija malignosti da bi se omogućila prikladna citološka klasifikacija ovih lezija. 
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700 1 |a Osorio-Morales, Lina  |4 aut  |9 HR-ZaNSK 
700 1 |a Pedraza-Ordóñez, Francisco  |4 aut  |9 HR-ZaNSK 
773 0 |t Veterinarska stanica (Online)  |x 1849-1170  |g 52 (2021), 4 ; str. 397-403  |w nsk.(HR-ZaNSK)000855872 
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