Current status of the lateral flow immunoassay for the detection of SARS-CoV-2 in nasopharyngeal swabs
Early detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and diagnosis of coronavirus disease 2019 (COVID-19) are priorities during the pandemic. Symptomatic and suspected asymptomatic individuals should be tested for COVID-19 to confirm infection and to be excluded from socia...
| Permalink: | http://skupni.nsk.hr/Record/nsk.NSK01001163335/Details |
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| Matična publikacija: |
Biochemia medica (Online) 31 (2021), 2 ; str. 230-239 |
| Glavni autori: | Somborac Bačura, Anita (Author), Dorotić, Marija, Grošić, Leonarda, Džimbeg, Monika, Dodig, Slavica |
| Vrsta građe: | e-članak |
| Jezik: | eng |
| Online pristup: |
https://doi.org/10.11613/BM.2021.020601 Elektronička verzija članka Elektronička verzija članka Elektronička verzija članka |
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| 008 | 230213s2021 ci |o |0|| ||eng | ||
| 024 | 7 | |2 doi |a 10.11613/BM.2021.020601 | |
| 035 | |a (HR-ZaNSK)001163335 | ||
| 040 | |a HR-ZaNSK |b hrv |c HR-ZaNSK |e ppiak | ||
| 041 | 0 | |a eng | |
| 042 | |a croatica | ||
| 044 | |a ci |c hr | ||
| 080 | 1 | |2 2011 | |
| 100 | 1 | |a Somborac Bačura, Anita |4 aut |9 HR-ZaNSK | |
| 245 | 1 | 0 | |a Current status of the lateral flow immunoassay for the detection of SARS-CoV-2 in nasopharyngeal swabs |h [Elektronička građa] |c Anita Somborac Bačura, Marija Dorotić, Leonarda Grošić, Monika Džimbeg, Slavica Dodig. |
| 300 | |b Ilustr. | ||
| 504 | |a Bibliografija: | ||
| 504 | |a Summary. | ||
| 520 | |a Early detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and diagnosis of coronavirus disease 2019 (COVID-19) are priorities during the pandemic. Symptomatic and suspected asymptomatic individuals should be tested for COVID-19 to confirm infection and to be excluded from social interactions. As molecular testing capacity is overloaded during the pandemic, rapid antigen tests, such as lateral flow immunoassays (LFIAs), can be a useful tool as they allow greater test availability and obtain results in a very short time. This short review aims to present the analytical properties of LFIAs in the detection of SARS-CoV-2 in nasopharyngeal swabs. Lateral flow immunoassay is a method that combines thin-layer chromatography and indirect immunochemical sandwich method and allows the detection of a specific SARS-CoV-2 antigen in nasopharyngeal swabs. Swab specimens should be adequately collected and tested as soon as possible. Users should pay attention to quality control and possible interferences. Antigen tests for SARS-CoV-2 show high sensitivity and specificity in cases with high viral loads, and should be used up to five days after the onset of the first symptoms of COVID-19. False positive results may be obtained when screening large populations with a low prevalence of COVID-19 infection, while false negative results may happen due to improper specimen collection or insufficient amount of antigen in the specimen. So as to achieve reliable results, a diagnostic accuracy study of a specific rapid antigen test should be performed. | ||
| 700 | 1 | |a Dorotić, Marija |4 aut |9 HR-ZaNSK | |
| 700 | 1 | |a Grošić, Leonarda |4 aut |9 HR-ZaNSK | |
| 700 | 1 | |a Džimbeg, Monika |4 aut |9 HR-ZaNSK | |
| 700 | 1 | |a Dodig, Slavica |4 aut |9 HR-ZaNSK | |
| 773 | 0 | |t Biochemia medica (Online) |x 1846-7482 |g 31 (2021), 2 ; str. 230-239 |w nsk.(HR-ZaNSK)000655372 | |
| 981 | |b Be2021 | ||
| 856 | 4 | 0 | |u https://doi.org/10.11613/BM.2021.020601 |
| 856 | 4 | 0 | |u https://www.biochemia-medica.com/en/journal/31/2/10.11613/BM.2021.020601 |y Elektronička verzija članka |
| 856 | 4 | 0 | |u https://www.biochemia-medica.com/en/journal/31/2/10.11613/BM.2021.020601/fullArticle |y Elektronička verzija članka |
| 856 | 4 | 1 | |y Digitalna.nsk.hr |
| 856 | 4 | 0 | |u https://hrcak.srce.hr/258878 |y Elektronička verzija članka |